The Human Cytomegalovirus Major Immediate-Early Proteins as Antagonists of Intrinsic and Innate Antiviral Host Responses
The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a a&d ej-123 decisive role in acute infection and its activity is an important indicator of viral reactivation from latency.Although a variety of gene products are expressed from this region, the 72-kDa IE1 and the 86-kDa IE2 nuclear phosphoproteins are the most